Lelio Orci

In a 2020 obituary, Orci was described as having a "strong, flamboyant personality" and "infectious enthusiasm" for science. He traveled rarely, instead working long hours in his laboratory. Orci had a wife, Catherine, and three children.

He studied medicine at the University of Rome, graduating in 1964. In 1966, he moved to the University of Geneva where he worked ever since. He was chair of the Department of Morphology from 1976 until his retirement in 2000, transitioning to professor emeritus. Orci is known for his work on cell and tissue biology using electron microscopy. In the first part of his research career, Orci's laboratory largely studied the organization of the pancreatic islet of Langerhans, as well as the secretion pathway of insulin from the beta cell. His group was the first to utilize immunogold labelling to localize intracellular proteins (published in 1980), and among the first to use freeze-fracture with electron microscopy to study a cell's internal organization. In 1984, he began collaborating with James Rothman on the work in vesicle trafficking that eventually earned Rothman, Randy Schekman, and Thomas C. Südhof the Nobel Prize.

Lelio Orci studied at Sapienza University of Rome. The recorded working language is Italian and English. The field of work recorded is medicine, endocrinology and diabetology. Distinctions recorded are Otto Naegeli Prize, King Faisal International Prize in Medicine, Minkowski Prize and Banting Medal.

• 1973: Minkowski Prize (European Association for the Study of Diabetes) • 1977: Nessim-Habif World Prize, University of Geneva • 1979: Fernand Tissot Prize • 1978: Mack-Foster Award (European Society for Clinical Investigation) • 1978: David Rumbough Award (American Juvenile Diabetes Foundation) • 1981: Banting Medal (American Diabetes Association) • 1983: Dale Medal (Society for Endocrinology) • 1985: King Faisal International Prize for Medicine • 1986: Otto Naegeli Prize for Medicine • 1986: Special Golgi Award (European Association for the Study of Diabetes) • 1987: Morgagni Medal (G.B. Morgagni International Prizes) • 1991: Elliot P. Joslin Award (Massachusetts Affiliate of the American Diabetes Association) • 1998: Member of the Senate of the Swiss Academy of Medical Sciences • 1998: Foreign Member of National Academy of Sciences • 1999: Fellow of the American Association for the Advancement of Science • 2000: Lucien Dautrebande Triennial Prize (The Physiopathology Foundation) • 2007: Leon Lombarti Prize • Order of Commander of Honor by the Italian Government The Lelio Orci Award for advances in cell biology was established in 2015.