Kaley Cuoco

Cuoco has also played Billie Jenkins in the fantasy series Charmed (2005–2006), voiced the title role in the animated series Harley Quinn since 2019, and played the lead role in the comedy thriller series Based on a True Story (2023). Her film work includes Quicksand: No Escape (1992) and Growing Up Brady (2000), as well as Virtuosity (1995), Hop (2011), The Wedding Ringer (2015), The Man from Toronto, Meet Cute (both 2022), and Role Play (2024). She received a star on the Hollywood Walk of Fame in 2014, and in 2017 founded Yes, Norman Productions.

Kaley Christine Cuoco was born on November 30, 1985, in Camarillo, California. She is the elder daughter of Layne Ann (née Wingate), a homemaker, and Gary Carmine Cuoco, a real estate agent. Her father is of Italian descent while her mother is of English and German ancestry. Her sister, Briana, is an actress and singer who competed on the fifth season of The Voice and co-starred with her on the HBO Max series The Flight Attendant and on Harley Quinn as Barbara Gordon/Batgirl. As a child, Cuoco was a ranked amateur tennis player, a sport she took up when she was three years old. She stopped playing at the age of 16 to pursue a career in acting.

Cuoco made her first feature film appearance as the young Karin Carter in the 1995 action thriller Virtuosity. In 2000, she portrayed former The Brady Bunch star Maureen McCormick in the TV film Growing Up Brady as well as starring in the Disney Channel original film Alley Cats Strike, and then in 2001, she appeared on the CBS sitcom Ladies Man. In September 2002, she began a starring role as Bridget Hennessy on the ABC sitcom 8 Simple Rules for Dating My Teenage Daughter (afterwards 8 Simple Rules). Bridget was the oldest child, despite Cuoco being six years younger than Amy Davidson, who played her younger sister. In addition to the final season of 8 Simple Rules, Cuoco had starring roles on the NBC miniseries 10.5, the ABC Family original film Crimes of Fashion, the independent film Debating Robert Lee, and in the film The Hollow at the same time. She also voiced the character of Brandy Harrington, a 14-year-old anthropomorphic mixed-breed dog, on the Disney Channel animated series Brandy & Mr. Whiskers. She voiced the character of Kirstee Smith in Bratz from 2004 to 2005. In the eighth season of the TV series Charmed, she appeared as Billie Jenkins, a powerful young witch with the powers of telekinesis and projection. Executive producer Brad Kern stated that Cuoco's character was initially brought in as a possible spin-off.

In October 2017, Cuoco founded Yes, Norman Productions, a television production company which entered an exclusive multi-year first-look production deal with Warner Bros. Television. Her first project through Yes, Norman was an adaptation of the book The Flight Attendant, written by author Chris Bohjalian, which was developed into a comedy-drama series of the same name. Cuoco starred in the series as Cassie Bowden, and also served as executive producer. The Flight Attendant premiered on November 26, 2020, on WarnerMedia's streaming platform HBO Max to widespread critical acclaim, and was renewed for a second season on December 18, 2020. In October 2018, it was announced that Cuoco would voice the title character of the DC Universe adult animation series Harley Quinn, and also serve as executive producer. The series premiered on November 29, 2019, to critical acclaim. In September 2020, it was announced that the series was renewed for a third season and would move to HBO Max. In April 2020, Cuoco joined the cast of the action comedy film The Man from Toronto as the female lead alongside Kevin Hart and Woody Harrelson. During May 2021, her production company expanded its Warner Bros. Television overall deal. In 2023, Cuoco launched an online pet product business called "Oh Norman!".

While working on The Big Bang Theory, Cuoco privately dated co-star Johnny Galecki for roughly two years, until December 2009. She later told CBS Watch in September 2010 that they have remained on good terms since ending their relationship. On September 13, 2010, Cuoco broke her leg in a horse-riding accident and missed the filming of two episodes of The Big Bang Theory. In October 2011, she became engaged to addiction specialist Josh Resnik, but ended their engagement by March 2012. She became engaged to professional tennis player Ryan Sweeting in September 2013, after three months of dating. They married on December 31, 2013, in Santa Susana, California. On September 25, 2015, it was announced that she and Sweeting had decided to divorce. The divorce was finalized on May 9, 2016. Cuoco began dating equestrian Karl Cook in late 2016. They became engaged on November 30, 2017, Cuoco's 32nd birthday, and were married on June 30, 2018. In September 2021, the couple announced their separation, stating "we have realized that our current paths have taken us in opposite directions". In June 2022, their divorce was finalized. Cuoco confirmed her relationship with actor Tom Pelphrey in May 2022. Five months later, she announced on Instagram that they were expecting their first child together. Cuoco gave birth to their daughter Matilda on March 30, 2023. They announced their engagement on August 14, 2024.