Tying the Knot with an Amagami Sister

An anime television series adaptation produced by Drive aired from October 2024 to March 2025.

The series follows Uryū Kamihate, a high school student who is aiming to pass the entrance exams to the Kyoto University's medical school. After living in an orphanage for much of his life following the death of his mother, he comes to live at Amagami Shrine, where the head priest asks him to marry one of his three granddaughters. Uryū and the Amagami sisters also have to contend with various issues, such as the shrine being in danger of closing down due to financial issues. Through flashforwards, it is implied that Uryū will eventually marry one of the sisters, even though he does not want to at all, and actively tries to avoid it at all costs.

Uryū Kamihate (上終 瓜生, Kamihate Uryū) Voiced by: Sōnosuke Hattori (voice comic), Ryōta Suzuki (anime) (Japanese); Branden Loera (English) A high school student aiming to enter Kyoto University's medical school. He was inspired to become a doctor after his mother's death. Despite being engrossed in studying most of the time, he managed to bond with the Amagami siblings in spite of their rough start and is destined to marry one of the siblings in order to continue the legacy of Amagami Shrine. Because he believes that God did not answer his prayers for his mother to get better, he initially does not believe in spirituality or religion, and hates the idea of relationships and having a significant other. Initially, he has no romantic feelings for any of the girls at all, and refuses to marry any of them, wanting to get away from them and the shrine as soon as possible. However, he eventually warms up to the girls and starts treating them better. He's very capable of doing household chores and cooking which the Amagami siblings adore very much. A frequent running gag of Uryu revolves around him getting caught in awkward situation where the Amagami siblings, Yuna in particular, keep on chiding him for being perverse. Yae Amagami (甘神 夜重, Amagami Yae) Voiced by: Miyu Tsuji (voice comic), Ai Kayano (PV1), Reina Ueda (PV2), Sumire Uesaka (anime) (Japanese); Monica Rial (English) The eldest daughter and an art major at a university with a playful personality. It is later revealed that she was actually adopted into the Amagami family and that her birth name is Reiko Ichijōji (一乗寺 澪子, Ichijōji Reiko). She has had a crush on Uryū since their short encounter few years ago, even though he does not reciprocate at all. Uryu's encouragement at the time led her to become more decisive and more carefree which allowed her to leave her dark childhood behind which helps shape her current personality. Yuna Amagami (甘神 夕奈, Amagami Yuna) Voiced by: Miyu Tsuji (voice comic), Sora Amamiya (PV1), Rie Takahashi (PV2), Kaede Hondo (anime) (Japanese); Hayden Daviau (English) The second sister, who has a tsundere personality. She excels academically despite having a poor command of English. She strives to preserve the legacy of the Amagami Shrine. She likes cats. Her birth name is Nadeshiko Kurama (鞍馬 撫子, Kurama Nadeshiko). Asahi Amagami (甘神 朝姫, Amagami Asahi) Voiced by: Miyu Tsuji (voice comic), Ayane Sakura (PV1), Ayana Taketatsu (PV2), Shion Wakayama (anime) (Japanese); Abigail Blythe (English) The youngest sister, who is a member of her school's track-and-field club. She is a mature middle school scholar despite her age. However, she has a complex about her small breasts. She fell in love with Uryū after the incident involving a time loop. It is later revealed that she too was adopted into the Amagami family and that she was born Miyuki Kiyomizu (清水 美雪, Kiyomizu Miyuki). Chidori Amagami (甘神 千鳥, Amagami Chidori) Voiced by: Sōnosuke Hattori (voice comic), Bin Shimada (anime) (Japanese); Kenny Green (English) The grandfather of the Amagami sisters and the chief priest of Amagami Shrine, who started caring for the sisters after the death of their mother. Mahiru Anekōji (姉小路 舞昼, Anekōji Mahiru) Voiced by: Nana Mizuki A doctor and the dormitory mother at the orphanage where Uryū used to stay at. She was the one who encouraged Uryū to stay at the Amagami Shrine. Yomiko Tsukigami (月神 読子, Tsukigami Yomiko) Voiced by: Yui Horie A senior priestess at the Tsukigami Shrine and a mentor to the Amagami sisters. Shirahi Tsuruyama (鶴山 白日, Tsuruyama Shirahi) Voiced by: Chika Anzai Uryu's childhood friend from the orphanage who shares his dream of entering Kyoto University's medical school. She has been in love with Uryu ever since the day she first met him at the orphanage, even though Uryuu has never reciprocated at all, and is dismayed by his newfound relationship with the Amagami sisters, wanting to get rid of them and have Uryuu all to herself. However, Uryu eventually rejects her and helps her realize her mistake, which leads to her mending her relationship with the girls and becoming a temporary maiden at the shrine. Miemon Kitashirakawa (北白川 巳右衛門, Kitashirakawa Miemon) Voiced by: Kōji Yusa Mitsuko Umenoki (梅ノ木 みつ子, Umenoki Mitsuko) Voiced by: Ayasa Itō Makoto Takeda (竹田 真, Takeda Makoto) Voiced by: Haruka Shiraishi Karen Matsugazaki (松ヶ崎 花蓮, Matsugazaki Karen) Voiced by: Natsuko Abe

Tying the Knot with an Amagami Sister is written and illustrated by Marcey Naito, who had previously worked as assistant under Negi Haruba on The Quintessential Quintuplets. It was originally published as a one-shot in Kodansha's shōnen manga magazine Weekly Shōnen Magazine on December 2, 2020, as part of a competition with three other one-shots where readers could vote on which would be serialized. It received the most votes among readers, and serialized in the same magazine from April 21, 2021, to August 27, 2025. To promote the manga, a voiced comic video was released on Weekly Shōnen Magazine's official YouTube channel on April 8, 2021. Kodansha has collected its chapters into individual tankōbon volumes. The first volume was released on July 16, 2021; advertisements featuring Ai Kayano, Sora Amamiya, and Ayane Sakura were released to commemorate the release of the first volume. The 22nd and final volume was released on October 17, 2025. The series is licensed in English digitally by Kodansha USA. During their panel at Anime NYC 2022, Kodansha USA announced a print release for Fall 2023.

An anime television series adaptation was announced during a livestream that celebrated the manga's second anniversary and Naito's birthday on April 21, 2023. It is produced by Drive and directed by Yujiro Abe, with Hiroshi Watanabe serving as assistant director, Yasuko Aoki writing the scripts, Haruko Iizuka designing the characters, and Ryo Kawasaki and Tomoyuki Kono composing the music. The series aired from October 2, 2024, to March 26, 2025, on TV Tokyo and its affiliates. For the first cour, the opening theme song is "Yawaku Koishite ~Zutto Bokura de Iraremasu yō ni~" (やわく恋して ～ずっと僕らでいられますように～), performed by Momoiro Clover Z, while the ending theme song is "Kimi ni Koi wo Musunde" (君に恋を結んで; lit. To Tie You With Love), performed by Sumire Uesaka, Kaede Hondo and Shion Wakayama as the three Amagami sisters. For the second cour, the opening theme song is "Pray Pray Pray", performed by Uesaka, Hondo and Wakayama as the three Amagami sisters, while the ending theme song is "Kami-sama no Iu Tōri!" (神様の言うとーり！; lit. As the Gods Say), performed by ≠Me. Crunchyroll streams the series. Plus Media Networks Asia licensed the series in Southeast Asia and broadcasts it on Aniplus Asia.