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One Chance

One Chance is an apocalyptic Flash game developed by Dean Moynihan and released on Newgrounds on December 2, 2010. It has been frequently cited in video games literature as an interesting and moving use of permadeath mechanic (permanent death). In the game, the player controls a scientist who has created a cancer-attacking "cure"; when it is released in a gas form it begins to cause the extinction of all life by unexpectedly targeting all living cells, rather than just cancer cells.

One Chance

Date
2010
Genre
puzzle video game

VALÉORINE Encyclopedia

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Documentary summary

One Chance is an apocalyptic Flash game developed by Dean Moynihan and released on Newgrounds on December 2, 2010. It has been frequently cited in video games literature as an interesting and moving use of permadeath mechanic (permanent death). In the game, the player controls a scientist who has created a cancer-attacking "cure"; when it is released in a gas form it begins to cause the extinction of all life by unexpectedly targeting all living cells, rather than just cancer cells.

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wikidata · Q18357302

In this article

  1. 01Making and history
  2. 02Reception, influence and legacy
  3. 03Notes, references and evidence

The Encyclopedia exists whether or not anything is for sale. Corrections are recorded rather than overwritten, and every version of this record is kept. Published 20 August 2026.

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