Fight Night Round 4

The game's featured boxers are Muhammad Ali and Mike Tyson. It contains 48 licensed boxers as well as several new modes, such as Legacy mode.

On May 14, 2009, a demo of the game was made available to those that had pre-ordered the game from GameStop, although it was made available for everyone to download later that month via Xbox Live or PlayStation Network. The demo features a three-round exhibition match between Ricky Hatton and Manny Pacquiao in the wake of their fight on May 2, 2009. A tutorial mode is also accessible at the beginning of the demo, which is featured in the final release. On August 27, 2009, a new updated demo was released. It now features a ten-round exhibition match between Muhammad Ali and Mike Tyson, in addition to the previous Hatton vs. Pacquiao match. It also features the return of the classic control scheme for the game where players can use the controller buttons for most controls instead of the right analog stick. This control scheme was originally in all previous Fight Night games, and it was brought into Fight Night Round 4 after fans were complaining about using the new control scheme and sufferings form clusters.

On July 27, 2009, the first piece of downloadable content for Fight Night Round 4 was released. It is free of charge, and includes a new training gym, new gameplay sliders, new equipment and an alternate version of Sugar Ray Leonard. Additional trunks, gloves and shorts were released along with face button control support in a free update at the end of August. The next piece of downloadable content, the Boxer Pack, contained Oscar De La Hoya, Vitali Klitschko and Wladimir Klitschko, as well as alternate versions of James Toney and George Foreman was released on 27 August and can be purchased through the PlayStation Store and Xbox Live Marketplace. In early December, a new pack including Bernard Hopkins, Evander Holyfield, Sonny Liston and two new modes (Old School Rules & Ring Rivalries) was released for the PlayStation 3 and Xbox 360.

On July 16, 2009, EA Sports released a themed game space for Fight Night Round 4 as an expansion to the EA Sports Complex in the European and North American versions of PlayStation Home. The game space is called "Club Fight Night" and features a Club-DJ mini-game with rewards, two video screens and seating for avatars. In an update, there would be a robot boxing mini-game available to play. This space was released in the Japanese version on October 9, 2009. On November 25, 2009, two producers of Fight Night Round 4, Mike Mahar and Brian Hayes, were in the space for a live chat with the Home community.

Physics based controls, Career mode is redesigned and replaced with legacy mode, players Can use photo game face to more easily put the player in the game, boxers can only block high and low, More focus on counter punching, User controlled cutman is removed and replaced with a point system, and Downloadable characters. Fight Night Round 4 Also added Flyweight and Bantamweight weight classes for the first time in a game. New boxers to the franchise allowed recreations of fights such as Ricky Hatton vs. Paulie Malignaggi, Marvin Hagler vs. Thomas Hearns and Fernando Montiel vs. Nonito Donaire. The game features 12 arenas, including Boardwalk Hall and the MGM Grand.