Aimee Mullins

She has periodically spoken at conferences, including TED Talks.

Mullins was born in 1976 in Allentown, Pennsylvania, to an Irish father Bernard Mullins from Crusheen, County Clare, Ireland and mother Bernadette Mullins. She was born with fibular hemimelia (missing fibula bones). As a result, both her legs were amputated below the knee when she was one year old. Her parents were told she would likely use a wheelchair for the rest of her life and never walk, but by the age of two she had learned to walk with prosthetic legs. She took up sports and acting at an early age. In 1993, Mullins graduated from Parkland High School in South Whitehall Township, Pennsylvania. She attended the Walsh School of Foreign Service at Georgetown University on a full scholarship, where she competed against nondisabled athletes in National Collegiate Athletic Association (NCAA) Division I track and field events. She is the first female amputee in history to compete in the NCAA and the first amputee in history (male or female) to compete in NCAA Division I track and field.

Mullins competed in the 1996 Summer Paralympics in Atlanta, where she ran the T42-46 class 100-meter sprint in 17.01 seconds and jumped 3.14 meters in the F42-46 class long jump. She retired from competitive track and field in 1998.

She was elected to represent American female athletes from 2007 to 2009 as Women's Sports Foundation president; the organization was founded by sports pioneer Billie Jean King. She remains a member of both its board of trustees and its athlete advisory panel for the Women Sports Foundation. Sports Illustrated magazine named her one of the "Coolest Girls in Sports". Mullins was included as one of the "Greatest Women of the 20th Century" in the Women's Museum in Dallas prior to the museum's closure. Along with Teresa Edwards, Mullins was appointed Chef de Mission for the United States at the 2012 Summer Olympics and 2012 Summer Paralympics in London. In 2012, she was appointed by then-Secretary of State Hillary Clinton to the State Department's Council to Empower Women and Girls Through Sports.

In 1999, she modelled for British fashion designer Alexander McQueen, opening his London show on a pair of hand-carved wooden prosthetic legs made from solid ash, with integral boots. She is able to change her height between 5 ft 8 in (1.73 m) and 6 ft 1 in (1.85 m) by changing her legs. She was on billboards in the U.S. as part of the "25 Years of Non-Uniform Thinking" campaign by Kenneth Cole in 2009. She was a face of L'Oréal Paris and was appointed a global L'Oréal ambassador in 2011.

Mullins appears periodically as a speaker on topics related to body, identity, design, and innovation. Her TED conference talks have been translated into 42 languages. She is credited as being one of the speakers that inspired Chris Anderson to purchase the TED conference from Richard Saul Wurman. She was named a TED "All-Star" in 2014.

Mullins began dating English actor Rupert Friend in 2013. The couple married in 2016.